James R. Downing, MD, received the inaugural AACR-St. Baldrick’s Foundation Award for Outstanding Achievement in Pediatric Cancer Research. American Association for Cancer Research and St. Baldrick’s Foundation created the award last year to honor a person whose contributions to pediatric cancer research led to fundamental improvement in the understanding and treatment of childhood cancer. Downing, president and…
(HealthDay News) — There has been a decrease in the risk for coronary artery disease among adult survivors of childhood cancer, according to a study published online Jan. 15 in The BMJ. Daniel A. Mulrooney, M.D., from St. Jude Children’s Research Hospital in Memphis, Tennessee, and colleagues conducted a retrospective cohort study at 27 institutions involving…
(HealthDay News) — Medical and ethical considerations of fertility preservation in children with cancer are addressed in a clinical report from the American Academy of Pediatrics, published online Feb. 18 in Pediatrics. Sigal Klipstein, M.D., from the Pritzker School of Medicine at the University of Chicago, and colleagues reviewed the medical aspects and ethical considerations of…
Through presentation of a hypothetical case of a child with B-cell acute lymphoblastic leukemia (ALL) undergoing treatment with chimeric antigen receptor T-cell (CAR-T) therapy at an academic hospital for children, the authors of this article, who were from the Seattle Children’s Hospital, Fred Hutchinson Cancer Research Center, and the Dana-Farber Cancer Institute, among other institutions,…
The Research to Accelerate Cures and Equity (RACE) for Children Act has the potential to substantially increase the number of required pediatric studies for novel anticancer drugs, according to an analysis of previously approved agents and RACE criteria. The RACE for Children Act was enacted in 2017 and will go into effect in 2020, with…
The Food and Drug Administration (FDA) has accepted for filing and granted Priority Review to Pedmark™ (sodium thiosulfate; Fennec Pharmaceuticals) for the prevention of ototoxicity induced by cisplatin chemotherapy in patients 1 month to <18 years of age with localized, non-metastatic, solid tumors. The New Drug Application (NDA) application is supported by data from 2 pivotal…
The high level of burnout among pediatric hematology/oncology fellows is associated with a decrease in empowerment, self-assessed humanism, and satisfaction in training, according to findings published in Pediatric Blood & Cancer. Investigators conducted a cross-sectional study of hematology/oncology fellows to assess the prevalence of burnout, the demographics associated with burnout, and the relationship between burnout and…
(HealthDay News) — Just one in five pediatric cancer patients enroll in clinical trials, down from 40 to 70 percent during the 1990s and 20 to 25 percent in the early 2000s, according to a study published online April 23 in PLOS ONE. Kelly E. Faulk, M.D., from the University of Colorado Aurora, and colleagues evaluated…
Data from MSK Kids pediatric program at Memorial Sloan Kettering Cancer Center in NYC suggest that pediatric patients with cancer may have risk for infection from SARS-CoV-2 that is similar to the risk for other children in the general population.1 However, infection among asymptomatic pediatric patient caregivers may be an important factor for infection control.…
Just the thought of a child getting cancer can be frightening and overwhelming. But while cancer can be life threatening, there’s encouraging news. Over the last few decades, improved therapies have helped childhood cancer survival rise to more than 80%. Many kinds of cancer can now be cured or controlled to help give children a…